Internship in vitro ADME of Biologics (6-12 months) - January 2025

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

At Roche, we believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives, and we are fearless in both making decisions and taking action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

In Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed. This position is located in ADME, a chapter within global Pharmaceutical Sciences, where the fate of new chemical entities and biologics is a primary focus. The ADME Chapter works throughout all stages of compound development, from lead optimization to candidate selection, all clinical  development phases to filing of new drug applications. We closely collaborate with our therapeutic areas and functions to convert hypotheses into innovative therapeutics.

Job mission

During the internship in in vitro ADME of biologics you will generate experimental data in order to assess the fate of new biologics R&D candidates in the disease area of neurosciences. The main focus will be to establish a new in vitro assay to study uptake and recycling of antibodies and better understand pharmacokinetics (PK) properties of drug candidates. 

Your impact

• Working with a multidisciplinary team, you will gain hands-on experience in state-of-the art methodologies (e.g. in vitro cellular models, ELISA and microscopy techniques) to assess PK properties of drug candidates. 

• You will learn how to develop, optimize and validate in vitro cellular models as well as quantitative methodologies to support drug development of biologics.

• You will document the experimental set-up, protocols and results with high scientific standards.

Your profile

You are an ambitious student currently enrolled in a life sciences program, preferably in molecular life science or biology, and pursuing either your bachelor's or master's degree. Furthermore:

• You have hands-on experience with common cell culture and molecular biology techniques, in particular with analytical techniques for the characterization and quantification of monoclonal antibodies (ELISA, microscopy, WB).

• You are eager to learn new in vitro techniques, comfortable with troubleshooting, and willing to repeat experiments multiple times as needed.

• You have an excellent command of both spoken and written English.

Duration

6–12 months – starting in January 2025

To be considered, please send us your complete application, including

• CV

• Motivation Letter (including desired start date & duration)

• A certificate of enrollment (if you are currently studying)

For non-EU/EFTA citizens: enrollment at the university for the entire internship is required and a letter from the university stating that the internship is mandatory for your studies. The letter should also specify the required length of the internship.  Please upload this mandatory letter and your enrollment certificate along with your CV and motivation letter.

Your location

The internship (100%) will be located in the Roche Pharma Research Center in Basel.

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.

Roche is an Equal Opportunity Employer.

Summary

• Location: Basel
• Type: Full time