Internship: CRISPR-Cas9 in human intestinal organoid in Basel (9 months)

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

At Roche, we believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives, and we are fearless in both making decisions and taking action. And we believe that good business means a better world.

That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

In the Immunology group, we are developing cutting edge therapies to treat inflammatory diseases. As a member of Immunology, you will be part of an international group that includes scientists and clinicians that are developing immunologic medicines for the future.

We are seeking a highly motivated master student for an internship position in CRISPR-Cas9 in human intestinal organoids.

In this position you will…

• Gain expertise in inflammatory bowel disease (IBD) research by using intestinal organoids to advance understanding of disease mechanisms and therapeutic strategies;

• Perform a genome-wide CRISPR-Cas9 screening;

• Develop and validate knock-out lines in human intestinal organoids to use in advanced in vitro systems;

• Contribute foundational knowledge that could lead to the development of new therapeutic strategies;

• Collaboratively design, execute and interpret experiments within a team environment;

• Potential co-authorship in a publication.
  

Who you are:

A highly motivated and enthusiastic master’s student with a strong desire to develop expertise in organoid genetic manipulation.

Furthermore, you are:

• Enrolled in a master program in life sciences (preferably in the area of molecular life science, biology, immunology, technology, pharmacy or biomedical engineering);

• Experienced with mammalian cell culture (experience in 3D culture is a plus);

• Knowledgeable of basic molecular biology techniques (e.g., PCR, DNA/RNA extraction, qPCR, sequencing, immunofluorescence microscopy);

• Familiar with genetic manipulation techniques and CRISPR-Cas9 (practical experience is a plus);

• Able to work collaboratively in a team environment;

• Proficient in English with strong written and oral communication skills.
  

To be considered, please send us your complete application merged into one PDF including 

• CV

• Motivation Letter (including desired start date; internship duration 9 months)

• A certificate of enrolment (if you are currently studying)

• For non-EU/EFTA citizens: due to regulations, enrolment at the university for the entire internship is required and a letter from the university stating that the internship is mandatory for your studies. The letter should also specify the required length of the internship.
  

We would like to inform you that, pending a successful initial review of your application, you will be invited to participate in an online assessment as part of the recruitment process.

Roche embraces diversity and equal opportunity in a serious way. We are dedicated to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be. 

For more information about opportunities for students and graduates, visit genext.roche.com

If you still have questions, then please check our FAQs and videos on careers.roche.ch/faq

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.

Roche is an Equal Opportunity Employer.

Summary

• Location: Basel
• Type: Full time