PhD Student - 3D organization of tumor microenvironment in primary and metastatic prostate cancer

(we are targeting applicants of all genders)
Fulltime | limeted | Announcement number: 347-2024

The Dr. Senckenberg Institut of Pathology (SIP) is a central unit of the University Hospital Frankfurt responsible for patient-oriented diagnostics and research. SIP utilizes a range of morphology and molecular-based cutting-edge technologies to analyze over 30.000 patient sampes every year. The scope of SIP ist o provide state-of-the-art diagnostics and develop novel biomarkers to improve patient care.

Project Discription

Prostate Cancer (PCa) is one of the most frequent and lethal tumor types in men.This project aims at uncovering the mechanisms through which PCa cells alter their local tissue microenvironment to promote primary tumor progression and metastatic dissemination. Using multiomics approaches and multiplex tissue imaging on patient samples and animal models, we will develop biomarkers for improved PCa classification and response to treatment. In addition, we will quantify the anatomical organization of the tumor microenvironment in a curated cohort of metastic PCa patients, in order to unravel and functionally assess crosstalk mechanisms that support metastasis.

Who You Are

• Master’s degree in Biomedical, Life Sciences or equivalent
• Basic experience in laboratory techniques (i.e. molecular biology)
• Background in immunofluorescence microscopy and prostate cancer are a plus
• Passions for discovery, collaborative spirit and good communications skills
• Good knowledge of MS-Office
• Good knowledge of spoken and written English
• Due to legal regulations, valid proof of measles immunity / measles vaccination is required.

What We Offer

• Collective agreement: In addition to an attractive salary based on a collective agreement with an annual special payment, 20 hours per week and 30 days of vacation, you benefit from long-term security through company pension schemes
  Mobility: Free public transport in all Hessen (Free State Ticket Hessen)
  Campus: Our attractive university hospital campus offers a modern cafeteria, various cafes, and opportunities to rest in numerous green spaces. A walk on the riverside of the Main offers relaxation during breaks
  Work-Life-Balance: Part-time employment is possible, we offer childcare in our daycare center (more information can be found here), child care during holidays
  Health Promotion: Benefit from our attractive health offers. We offer regular online and face-to-face courses on
  nutrition, relaxation, sports and exercise.
  Professional development: Internal and external training for your professional development 

Disabled applicants are preferred if they have the same personal and professional qualifications.

Join Our Team!

Use the time until May 10, 2024 to apply. Please submit your online application including a possible starting date and your salary expectations. For further information regarding the position and project, please contact Mrs. Marleen Mildenberger (phone: 069-6301 5444).