The group of Dr. Daniele Bano investigates molecular mechanisms associated with neurodegenerative diseases. We are interested to understand the genetic and non-genetic basis underlying the heterogeneous clinical manifestations associated with inherited mitochondrial lesions. Consistent with our previous published studies (see ), one goal is to identify disease modifiers that can counteract aberrant mitochondrial metabolism.

Tasks:

The team is searching for a highly motivated and science-driven PhD student to study the cellular response to aberrant electron transport chain biogenesis and/or ATP synthase inhibition. Using a combination of cultured cells, yeast (in collaboration with Prof. Thomas Becker, Bonn) and Caenorhabditis elegans, the newly recruited team member will elucidate the mitochondrial complexome of mitochondrial mutant cells. Furthermore, s/he will investigate the compensatory metabolic rewiring that promote cell resilience and animal survival.

Profile:

We are searching for a doctoral candidate with a recent Master degree (or equivalent) and a background in experimental Life Science disciplines. The successful candidate has good communication skills, is a team player and has the commitment to comply with deadlines that are essential for the success of the study.

• Innovation and internationality - a forward-looking infrastructure, modern laboratory and office equipment, software tools and the opportunity for international exchange with your colleagues from 65 nations
• Work-life balance - we reconcile work and private life with flexible working hours,  30 days' holiday (On top free on Christmas Eve and New Year's Eve) and subsidised job/ Germany ticket options
• Family-conscious corporate culture - because we know that family is important, we support you with parent-child offices, family services and daycare co-operations
• Health promotion – through our extensive range of company health programmes, in cooperation with Sozialwerk.Bund
• Focus on development - training programmes tailored to your individual needs and annual HR-development meetings for concrete prospects and potential development
• A position initally limited to three years
• Personalised Onboarding - for a good start to your new professional challenge
• A feel-good working environment - our Bonn employees enjoy a campus surrounded by greenery, with on-site parking and public transport connections as well our company restaurant

Please submit your application inlcuding CV, motivation letter and references via the link below.

You will obtain special skills and knowledge for your scientific qualification during your activities at DZNE. The DZNE is an equal opportunity employer. It especially welcomes and encourages disabled individuals to apply.